I think Asperger's might be culture-bound
in the sense that a person who had the exact same traits and grew up in another culture might fit in perfectly, perhaps even better
, than what Americans would call a neurotypical.
People like us stand out in America precisely because American culture values the very things that don't come naturally to us, while devaluing the things that do. American religion (Protestantism, especially of the revivalist/emotionalistic variety) also seems to be uniquely ill-suited to people on the spectrum.
This cartoon by Thomas Nast seems to exemplify the American worldview. Notice how the "nerd" is characterized negatively and the brawny boxer is held up as the ideal man.
But in another country, the shoe might end up on the other foot.