That's mean it is the earliest schizm in the church history!!
At that time, was this a separation between Oriental Orthodoxy and Parish of Constantine?
Well, in 428 (or 429) the Persian-Assyrian Church schismed from the Imperial Church, so that's even earlier. Then we have the schism of the Ebionites which dates to the 2nd century.
The seperation between the OO has not always been between the Oriental Patriarchates (Antioch and especially Alexandria on the one side) and Constantinople on the other side. Constantinople switched back and forth between the OO and the Chalcedonians. The only Patriarchate which was consistently Chalcedonian was Rome.