The Cherokee script, invented by Sequoyah
ca. 1821. At the time he created the Cherokee syllabary, he could not read or write any other script (although he did have copies of the Bible and other documents, hence the use of Roman-derived symbols, albeit signifying different sounds).
Some of the more unusual characters almost look Armenian or Ge'ez, sort of.
If anyone else has anything interesting to post about (or in) this language, feel free to do so.
Another script, Vai
(used in Liberia), is believed to have been derived from it. There were a few Cherokee who emigrated to Liberia and married into the Vai tribe.