Also to those who PMed, in case I don't reply to those soon.
PtA, I figured you had some serious insight here. I am guessing you are still crunching those numbers.
Aside from the obvious major statistical categories (win percentages, turnover differential, scoring differential, rushing yards, etc.), statistics are really not good predictors for a football game, at least not in any way that would allow you to combine them and "crunch" them.
A better and easier way to do it would be to match up individual players where applicable, and then to match up team tactics (e.g. team A's pass offense vs. team B's pass defense). The latter in particular requires watching the teams at a level higher than the "analysis" on ESPN would lead one to believe.
Unfortunately I've only been paying detailed attention to one team so far this season, so there's not much I can tell you about most of the upcoming games.