From the Apostolic Canons:http://www.voskrese.info/spl/aposcanon.html
An eunuch, if he has been made so by the violence of men [some mss. add: or if his virilia have been amputated] in times of persecution, or if he has been born so, if in other respects he is worthy, may be made a bishop.
He who has mutilated himself, cannot become a clergyman, for he is a self-murderer, and an enemy to the workmanship of God.
If any man being a clergyman shall mutilate himself, let him be deposed, for he is a self-murderer.
If a layman mutilate himself, let him be excommunicated for three years, as practising against his own life.